Agencia Costarricense de Investigaciones Biomédicas (ACIB) is a research center in health and prevention of cancer, which began in the province of Guanacaste, Costa Rica in 1993 under the name Proyecto Epidemiológico Guanacaste (PEG). In a study of over 5,000 women about…
Agencia Costarricense de Investigaciones Biomédicas…
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Costa Rica vaccinated and not vaccinated against Human Papilloma Virus” (conducted in collaboration with the National Cancer Institute, USA) Study to continue evaluating for 10 years the effectiveness of the human papillomavirus vaccine in healthy young women in Costa Rica.View more
Of anal human papillomavirus infection and associated disease among women participating or who has participated in the “Extended follow-up of young women in Costa Rica who received vaccination against human papillomavirus types 16 and 18 and unvaccinated controls” study (in collaboration with the National Cancer Institute of EEUU). Study on anal infection by Human Papilloma […]View more
Proyecto Epidemiológico Guanacaste, Fundación INCIENSA, San José, Costa Rica—Bernal Cortés (specimen and repository manager), Paula González (LTFU: co-principal investigator), Rolando Herrero (CVT: co-principal investigator), Silvia E. Jiménez (trial coordinator), Carolina Porras (co-investigator), Ana Cecilia Rodríguez (co-investigator).View more
Of the mouth, skin, colon, vagina and penis, and time evaluation of the diversity of organisms at each site (conducted in collaboration with the National Cancer Institute, USA) Study to evaluate the set of microorganisms that are normally found in the mouth, skin, colon, vagina and penis and how they change between different people and […]View more
Between the Cohort of the Natural History Study of the Guanacaste Project and the National Registry of Tumors of Costa Rica”, in collaboration with the National Cancer Institute of the United States. Study to compare the database of the Natural History Study of the Human Papilloma Virus against the base of the National Tumor Registry […]View more
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As for facilities referred to PEG, there are six clinics distributed in different parts of the province of Guanacaste and Puntarenas, such as clinic Liberia, Cañas, Nicoya, La Cruz, Santa Cruz and Puntarenas as well as an office building and laboratories in the Solarium complex in Guanacaste Liberia. Also an office building in Rohrmoser, San José.
Within the resources PEG has a number of laboratories among them:
In this laboratory liquid monolayer cytology or cytology is performed, technique which has advantages in clarity, reliability and facility versus conventional cytology (Pap). With this technique after a series of processes, the cells are filtered and transferred to slides in a very thin layer whose thickness has only one representative cell level (monolayer) of the whole sample, which are subsequently stained for analysis by a specialist.
This laboratory specializes in processing and LEEPS biopsies from women referred from colposcopy. In this laboratory tissues are processed in order to fix them in paraffin blocks later to make slides, which can have a p16 immunohistochemistry staining or stained with hematoxylin for diagnosis by a Pathologist.
Our laboratory has one of the most modern tests for detection of HPV: Aptima, which takes HPV RNA isolated from cells, which captures and amplifies it to be detected by the combination of reagents that produce chemiluminescence. Detects the presence of 14 types of HPV in a sample, including high-risk (HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68 and 66). In addition, this test has the option of genotyping for HPV types 16 and 18/45. This technique is approved by the FDA for the detection of HPV.
This laboratory specializes in processing blood samples and cervical, anal and oral samples. Has cameras type II laminar flow, centrifuges with temperature control, air extractors, among others.
An entity that receives, stores, processes and / or distributes biological samples, as needed. It includes physical location as well as the full range of activities associated with its operation.
Its purpose is to keep biological samples and associated information, for future use in research, ensuring quality. The biorepository of PEG contains biological samples, including blood, secretions, and tissue aliquots taken with the consent of the participants.
However, for PEG its main resource is a team full of highly trained professionals in each of their areas.